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Total 46 questions
Exam Code: NAPLEX                Update: Sep 13, 2025
Exam Name: North American Pharmacist Licensure Examination

NABP North American Pharmacist Licensure Examination NAPLEX Exam Dumps: Updated Questions & Answers (September 2025)

Question # 1

In Normal distribution, what percentage of the sample is found within 2 standard deviation of the mean?

A.

68%

B.

95%

C.

99%

D.

100%

E.

72%

Question # 2

What is the Osmolarity in mOsm/L of 40mEq of KCl in 100ml sterile water? (Molecular weight of KCl is 74.5gm/ mol.)?

A.

400mOsm/L

B.

800mOsm/L

C.

80mOsm/L

D.

200mOsm/L

E.

1600mOsm/L

Question # 3

LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.

His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN’s medication includes Dexamethasone 8mg iv q6h with taper dosing, Ondansetron 4mg iv q6h prn for N/V, Levothyroxine 0.075mg po daily, Lisinopril 10mg po daily, Citalopram 20mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10mg suppository daily prn for constipation, Famotidine 20mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500mg po bid, D51/2NS with 20K at 125mls/hour and Hydromorphone PCA at 0.2mg/hour of basal rate, demand dose 0.1mg. lock-out

every 6min, one hour limit 2.2mg/hour. Pertinent morning labs includes serum creatinine 1.4mg/dl, Mg 1.5mg/ dl, K 5.0mmol/L, Na 135mmol/L. The bioavailability of levothyroxine is roughly 50%.

The physician requests you for a dose recommendation to convert her home dose of 75mcg po daily to intravenous.

What would be the appropriate intravenous dose?

A.

37.5mcg

B.

75mcg

C.

75mg

D.

150mcg

E.

37.5mg

Question # 4

A 22-year-old woman adopted a cat. Shortly thereafter, she developed itchy eyes and persistent rhinorrhea. She was clearly allergic to the pet, but desperately wanted to keep it. She tried taking diphenhydramine, but it had intolerable side effects.

Which of the following is a common effect of this type of medication?

A.

Decreased intraocular pressure

B.

Bradycardia

C.

Xerostomia

D.

Diarrhea

E.

Excessive sweating

Question # 5

Concomitant use of warfarin and omeprazole is associated with increased INR and prothrombin time(PT). What enzyme dose the omeprazole inhibits that is metabolized by warfarin?

A.

CYP3A4

B.

CYP2C9

C.

CYP2C19

D.

CYP2D9

E.

CYP1A2

Question # 6

Which of the following would you use for aspiration pneumonia with an intention to cover anaerobes?

A.

Piperacillin-Tazobactam

B.

Cefepime

C.

Ampicillin-sulbactam

D.

Cefazolin

E.

Levofloxacin

Question # 7

JT is a 58-year-old women who is on vancomycin empirically for pyomyositis confirmed by MRI. Surgical debridement has successfully removed infected tissue and pus. C&S of the infected tissue comes back MSSA sensitive to everything on the panel. JT is allergic to PCN (rash), she has had cephalosporin for her UTI in the past with no problem.

What would be the most appropriate antibiotics to switch to while JT is still in the hospital?

A.

Oxacillin

B.

Doxycycline

C.

Ceftaroline

D.

Daptomycin

E.

Cefazolin

Question # 8

A patient who weighs 80kg is ordered Esmolol at 50mcg/kg/min. Esmolol comes in 2500mg/250 ml NS premixed bags. What is the infusion rate in mls/hr?

A.

20mls/hr

B.

6mls/hr

C.

8mls/hr

D.

24mls/hr

E.

32mls/hr

Question # 9

Pyridoxine is often used in pregnancy to manage which of the following conditions?

A.

Hot flushes

B.

Diarrhea

C.

Nausea / vomiting

D.

Mood disturbances

E.

Insomnia

Question # 10

Select the class of Anti-diabetic medication that works in the specified organto prevent hyperglycemia. Select all that applies. Fat Tissue (H)

A.

Sulfonylureas

B.

Alpha- Glucosidase Inhibitors

C.

DPP4 Inhibitors

D.

Glucagon-like peptide-1 receptor agonists

E.

Thiazolidinediones

F.

Biguanide

G.

SGLT2 inhibitors

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Total 46 questions

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